^∞ Every woman is unique and every woman experiences menopause and its symptoms differently. Every woman's experience with Amberen® will be unique as well. The statements we make regarding Amberen's menopausal and perimenopausal symptom relief benefits are supported by the results of ingredient manufacturer sponsored randomized, double-blind, placebo-controlled, human clinical trials. Amberen's products' clinical trials include three recent trials, two on Amberen Menopause dating from 2014-15 and 2015-16, and another on Amberen Perimenopause dating from 2019-2020. The Amberen^® Menopause trials involved 102 and 125 menopausal women, respectively, aged 42-60 years, with mild to moderate menopausal symptoms, evaluating the efficacy of Amberen^® Menopause in the treatment of climacteric complaints over the course of 90 days. Both of the studies' results showed that Amberen helped restore hormonal balance by supporting the endogenous production of estrogen and that when compared with placebo users experienced statistically significant relief from common menopausal symptoms, including, but not limited to, hot flashes, night sweats, irritability, mood swings (as measured by relief from “feeling unhappy and depressed”, “crying spells”, and “loss of interest in most things” symptomologies), weight management (as measured by changes in weight, BMI, and hip and waist circumference analyses), difficulty sleeping, stress and anxiety, difficulty concentrating, fatigue and low energy, headaches, muscle and joint aches and loss of sexual interest. Statistically significant results typically occurred between 30 through 90 days of continuous use. The Amberen^® Perimenopause trial involved 105 perimenopausal women, aged 36-50 years, with mild to moderate perimenopausal symptoms, evaluating the efficacy of Amberen^® Perimenopause in the treatment of perimenopausal symptom complaints over the course of 180 days (90 days of intervention/90 days of observation). The study's results showed that Amberen Perimenopause helped restore hormonal balance by supporting the endogenous production of estrogen and that when compared with placebo users experienced statistically significant relief from common perimenopausal symptoms, including, but not limited to, hot flashes, night sweats, irritability, mood swings (as measured by relief from “feeling unhappy and depressed”, “crying spells”, and “loss of interest in most things” symptomologies), difficulty sleeping, stress and anxiety, fatigue and low energy, headaches, muscle and joint aches and loss of sexual interest. Statistically significant results typically occurred between 30 through 90 days of continuous use. (Radzinskii, V. E., et al. Gynecological Endocrinology 32.sup2 (2016): 64-68. Radzinski V. et al., Menopause. Vol. 24, No. 12 (2017): 1456-1457. Kuznetsova et al., Obstetrics and Gynecology (2016) 5:126- 33).

^‡ No adverse side effects were observed during clinical studies. Caution: Amberen products are not intended for use by pregnant or nursing women. Do not take if you have severe hypertension. If you are taking prescription medication or have any medical condition, consult your doctor before use. Discontinue use and consult your doctor if you have any adverse reaction.

^{^} In a clinical trial a statistically significant number of Amberen Perimenopause group participants reported a return of their period to a more regular pattern.
Notice: Women in perimenopause can become pregnant, discuss contraception options with your doctor.

^** Individual results will vary. These endorsements and testimonials are provided as a means for customers to share their experiences using Amberen with other women and are not provided or intended to be interpreted as claims that Amberen will provide the same benefits to all customers. The endorsements and testimonials are displayed verbatim except where edited for privacy reasons, length or to correct grammatical or typing errors, and not all endorsements or testimonials are shown in their entirety as privacy concerns, space availability and relevancy at times require minor editing prior to being displayed. Endorsements and testimonials are never edited, however, in a way that would change their substantive meaning or essence. Amberen.com does not manage the reviews on any retailer site. Over 14,000 5-star reviews as of 03.09.23 on Amazon.com. Overall average ratings will vary on each online review platform.

^ϕ None of Amberen's ingredient formulations contain estrogen or other hormones of any kind. Notice for Healthcare Professionals: Clinical study results have shown, when taken as directed, Amberen products increase endogenous estrogen levels.

^◊ Based on survey conducted on www.amberen.com between July and September 2015 of 1103 actual Amberen customers who completed a 90-day course who responded "Yes" to the question "Did Amberen work for you in relieving menopause symptoms?"

^†† NurseAid^TM agents do not provide medical advice and should never be used as a substitute or alternative to seeking professional medical advice and treatment.

^≠IRI US MULO 52 wks unit & dollar sales 07.11.21 by UPC (Amberen Menopause Relief)

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