Unique & Safe Ingredients

Amberen Perimenopause is an innovative succinate-based formulation designed especially for perimenopausal women. It includes a blend of antioxidants, amino acids, minerals, vitamin E, and our unique Smart B® Complex. Together, these ingredients work in synergy to relieve multiple perimenopause symptoms by helping to restore hormonal balance and menstrual regularity.^*

Amberen Perimenopause Capsules
Amberen Perimenopause Box
Amberen Perimenopause Supplements Amberen Perimenopause Supplements

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Mitochondrial Antioxidant:

  • Ammonium succinate blocks the activity of free radicals and prevents them from causing damage. Energy production: many studies have shown that the human aging process contributes to the decline of mitochondrial energy metabolism and increased mitochondrial oxidative stress. Succinate molecules act as fuel for mitochondria and help stabilize their energy-production processes.
  • Disodium fumarate is a molecule that ultimately transforms into a mitochondrial antioxidant.

Toxic By-Products Elimination:

  • Ammonium succinate promotes the elimination of toxic by-products.

Calcium Disuccinate:

  • A source of calcium vital for bone-tissue formation, nerve-signal transmission, muscle contractions, and blood clotting. The calcium disuccinate molecule is a chelating agent and aids in the transporting of calcium before it is absorbed in the digestive system.

Magnesium Disuccinate:

  • The source of magnesium required for the activity of hundreds of enzymes, muscle relaxation, bone and heart health, the conduction of nerve impulses, maintaining blood pressure, and protein production.

Zinc Difumarate:

  • A zinc source found in the active centers of over 300 enzymes, which require zinc for proper functions. Zinc plays a key role in the synthesis and secretion of many hormones (e.g., insulin), functions of the immune system, normal growth and development, carbohydrate metabolism, and DNA synthesis.


  • An amino acid involved in the processes regulating brain-cell activity.
  • In combination with magnesium, it makes brain mitochondria more resistant to low-oxygen conditions (hypoxia), which, in turn, results in the normalization of the psycho-emotional balance in the body.

Monosodium L-glutamate:

  • An amino acid salt that functions as a neurotransmitter and regulates the chemical reactions of transamination. For more details on this ingredient, please visit the FDA website.
  • Amberen contains a safe, small amount — 40 mg per each serving.

Vitamin E:

  • In its form as tocopheryl acetate, is a fat-soluble, natural antioxidant that prevents lipid peroxidation of cell membranes. Cell organelles and, most importantly, the DNA contained in the nucleus relies on the membrane to protect them.
  • Antioxidative properties of tocopheryl, supplemented by water-soluble succinate anions, promote the stabilization of the membrane structure, as well as general cell functions.

Vitamin B1:

  • B1 plays a crucial role in nerve, muscle, and heart function. It also helps to transform carbohydrates into energy.

Vitamin B2:

  • B2 breaks down proteins, fat, and carbohydrates in the body.

Vitamin B6:

  • B6 helps with metabolism and the creation of red blood cells.

Vitamin B9:

  • B9 is essential for the body to metabolize amino acids for the synthesis and repair of DNA.

Vitamin B12:

  • B12 helps to produce red blood cells as well as aid in nervous system support.

These five B vitamins and disodium fumarate make up the Amberen Perimenopause Smart B® Complex.*

Mary Lou Retton Mary Lou Retton
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